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Fig. 9 | Cancer Nanotechnology

Fig. 9

From: HB5 aptamer-tagged graphene oxide for co-delivery of doxorubicin and silibinin, and highly effective combination therapy in breast cancer

Fig. 9

Gene expression analysis of CDK2 (A) and Rb (B) genes in SK-BR-3 and MCF-7 cells using the RT-qPCR technique. The protein expression of CDK (C, D) and Rb (E, F) in SK-BR-3 and MCF-7 cells using western blot analysis. The analyzed values are shown as mean ± SD. (n = 3), *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 vs control. cGO: carboxylated graphene oxide; Apt: aptamer; DOX: doxorubicin; Sili: silibinin

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