Fig. 2

In vivo biodistribution of DiR-labeled nanoliposomes administered subcutaneously to mice. A Whole-body images of DiR-labeled liposomes at various time points after treatment. B Ex vivo imaging of mice liver, LNs, spleen, feet, and hands 96 h following the liposome injection. The quantitative fluorescence intensity of DiR-labeled liposomes throughout the body C, as well as the signal emitted by LNs and other organs D, was measured. The fluorescence intensity scale is also shown