Nanoliposomal VEGF-R2 peptide vaccine acts as an effective therapeutic vaccine in a murine B16F10 model of melanoma

Table 2 Physicochemical characteristics of the liposomal formulations

Formulation	Lipid composition	Lipid Molar Ratio	Z average (nm)^a	Z potential (mV)^b	PDI^c	% EE^d
Naïve Liposome	DMPC:DMPG:DOPE:Chol	60:8:20:12	128 ± 0.6	− 17 ± 0.1	0.28	–
Lip-V1	DMPC:DMPG:DOPE:Chol	60:8:20:12	138 ± 0.8	− 17 ± 0.1	0.26	74.1 ± 2.2
Lip-V2	DMPC:DMPG:DOPE:Chol	60:8:20:12	141 ± 0.9	− 29 ± 0.2	0.27	66.8 ± 4.7
Lip-V3	DMPC:DMPG:DOPE:Chol	60:8:20:12	139 ± 0.5	− 17 ± 0.4	0.27	74.8 ± 0.7

The results of triple measurements of each formulation are reported. The information is displayed as mean ± Standard deviation (S.D)
^aThe size of liposomes (Z average)
^bThe charge of liposomes
^cPolydispersity index
^dEncapsulation Efficiency (%)

ISSN: 1868-6966