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Fig. 1 | Cancer Nanotechnology

Fig. 1

From: Co-delivery of curcumin and si-STAT3 with a bioinspired tumor homing for polydopamine nanoparticles for synergistic osteosarcoma therapy

Fig. 1

The characterization of CPDA/siSTAT3@SCM NPs. A UV–Vis absorbance spectra of CUR, PDA NPs, and PDA–CUR NPs. B Fluorescence of 100 nM Cy3-siSTAT3 mixed with different concentrations of PDA NPs (0, 0.05, 0.10, 0.20, 0.40, and 0.80 μg/μL). C TEM images of the synthesized CPDA/siSTAT3 NP, SCM vesicle, and CPDA/siSTAT3@SCM NP. Scale bar = 50 nm. D SDS-PAGE-based protein analyses of SCM, CPDA/siSTAT3 NPs, and CPDA/siSTAT3@SCM NPs. E Intracellular co-localization of MSC membrane (red) and PDA/siSTAT3core (green). F Surface zeta potential of different formulations

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Cancer Nanotechnology

ISSN: 1868-6966

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