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Fig. 2 | Cancer Nanotechnology

Fig. 2

From: Co-delivery of curcumin and si-STAT3 with a bioinspired tumor homing for polydopamine nanoparticles for synergistic osteosarcoma therapy

Fig. 2

Phagocytosis and safety evaluation of CPDA/siSTAT3@SCM NPs. A Cellular uptake of CPDA/siSTAT3 NPs and CPDA/siSTAT3@SCM NPs at 24 h analyzed by CLSM. Scale bar = 50 μm. B Hemolysis assay of multiple densities of CPDA/siSTAT3@SCM NPs. C Relative STAT3 mRNA expression in MG63 cells after transfection with naked siSTAT3, Lipo3k/siSTAT3, or CPDA/siSTAT3@SCM NPs. D Fluorescence microscopy images of MG63, hFOB1.19, LO2, and RAW264.7 cells after 4 h incubation with Cy3-labeled CPDA/siSTAT3 NPs and CPDA/siSTAT3@SCM NPs (nucleus visualized with blue Hoechst33342 dyes; NPs visualized with red Cy3 dyes). Scale bar = 100 μm

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Cancer Nanotechnology

ISSN: 1868-6966

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