Fig. 6

Effect of fractionated CP-GNP on tumor growth and general toxicity. A Tumor growth in free CP-treated, CP-GNP-treated and untreated mice. Growth normalized to initial volume. p < 0.05 for *free CP-treated and ^#CP-GNP-treated vs. untreated; Student’s t-test. B. Kaplan–Meier survival curve showing prolonged survival of CP-GNP-treated mice as opposed to CP-treated mice. C Weight levels in treated and untreated mice. *p < 0.05 free CP treated vs. untreated (days 4–20); ^#p < 0.05 CP-GNP treated vs. untreated from days 13–20 (Student’s t test). Weight normalized to initial weight. Results presented as mean ± SEM