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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: ΔPSap4#5 surface-functionalized abiraterone-loaded nanoparticle successfully inhibits carcinogen-induced prostate cancer in mice: a mechanistic investigation

Fig. 6

Cell cytotoxicity, apoptosis, and mitochondrial membrane depolarization assay of ABR, ABR-NP, and Apt-ABR-NP evaluated in vitro. A IC50 values of ABR, ABR-NP, and Apt-ABR-NP on LNCaP and B PC3 cells after 48 h of treatment (data show mean ± SD, n = 3; * indicates p<0.05 when compared with ABR-treated group of mice). C Induction of apoptosis in LNCaP cells after treatment with ABR, ABR-NP, and Apt-ABR-NP for 48 h. D Mitochondrial membrane depolarization after 48 h of treatment, with ABR, ABR-NP, and Apt-ABR-NP for 48 h

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Cancer Nanotechnology

ISSN: 1868-6966

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