Organ/tissue | %ID of 99mTc-ABR-NP in CRPC mice | %ID of 99mTc-Apt-ABR-NP in CRPC mice | ||||
---|---|---|---|---|---|---|
1 h | 2 h | 5 h | 1 h | 2 h | 5 h | |
Blood# | 3.882 ± 0.01 | 3.601 ± 0.22 | 3.228 ± 0.28 | 4.156 ± 0.31 | 3.946 ± 0.31 | 3.644 ± 0.42 |
Heart | 0.545 ± 0.12 | 0.602 ± 0.05 | 0.664 ± 0.04 | 0.712 ± 0.03 | 0.722 ± 0.07 | 0.730 ± 0.04 |
Liver | 20.12 ± 2.10* | 24.55 ± 2.00* | 22.44 ± 4.34* | 23.60 ± 2.55* | 26.04 ± 2.01* | 30.58 ± 1.80* |
Lungs | 0.563 ± 0.21 | 0.578 ± 0.23 | 0.606 ± 0.32 | 0.688 ± 0.20 | 0.894 ± 0.20 | 1.142 ± 0.33 |
Stomach | 0.448 ± 0.16 | 0.382 ± 0.10 | 0.404 ± 0.11 | 0.725 ± 0.10 | 0.784 ± 0.11 | 0.942 ± 0.20 |
Intestine | 2.762 ± 0.51 | 2.920 ± 0.31 | 3.752 ± 0.30 | 3.114 ± 0.12 | 3.205 ± 0.55 | 4.025 ± 0.62 |
Kidney | 3.452 ± 0.30 | 4.348 ± 0.42 | 7.88 ± 0.528* | 4.565 ± 0.45* | 7.14 ± 0.642* | 10.24 ± 0.47* |
Prostate | 1.642 ± 0.21 | 1.811 ± 0.16* | 2.313 ± 0.22* | 2.256 ± 0.30 | 2.622 ± 0.24* | 3.142 ± 0.36* |
Urine | 26.56 ± 3.89* | 30.56 ± 2.18* | 32.44 ± 2.14* | 30.12 ± 1.55* | 33.56 ± 2.51* | 37.12 ± 3.18* |