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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Boosting nuclear-targeted photothermal-chemotherapy by NIR-responsive hybrid membrane camouflaged nanotherapeutics

Fig. 4

In vitro antitumor activity of PB@DN@M NPs. a Cell viability of HepG2 cells after different treatment. ****P < 0.0001 b Fluorescent images of intracellular ROS accumulation during the DOX, PB@DN@M and PB@DN@M + NIR-induced cell death. Scale bar: 50 μm. c Mitochondrial membrane potential changes of HepG2 cells during DOX, PB@DN@M and PB@DN@M + NIR-induced cell death measured by JC-1 kit. d Fluorescent images of HepG2 cells stained with calcein-AM (green, live cells) and PI (red, dead cells) after PB@DN@M with/without NIR treatment. Scale bar: 50 μm

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