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Fig. 4 | Cancer Nanotechnology

Fig. 4

From: Targeting and internalizing PEGylated nanodrugs to enhance the therapeutic efficacy of hematologic malignancies by anti-PEG bispecific antibody (mPEG × CD20)

Fig. 4

mPEG × CD20 BsAb enhances the internalization of Lipo-DiD by receptor-mediated endocytosis. Raji cells were incubated with αCD20/Lipo-DiD, αDNS/Lipo-DiD, and a receptor-blocking group, Ofatumumab (anti-CD20 Abs), in combination with αCD20/Lipo-DiD. This was followed by supplementation with DAPI and LysoTracker Green DND-26 and the samples were observed using a confocal microscope. DAPI (blue), LysoTracker Green DND-26 (green), and Lipo-DiD (red) stain for the nuclei, lysosome, and Lipo-DiD, respectively. White scale bars represent 20 μm

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Cancer Nanotechnology

ISSN: 1868-6966

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