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Fig. 5 | Cancer Nanotechnology

Fig. 5

From: Utilizing two-dimensional monolayer and three-dimensional spheroids to enhance radiotherapeutic potential by combining gold nanoparticles and docetaxel

Fig. 5

Radiation response in monolayer. a, b Normalized PrestoBlue proliferation assay after 6 days following radiation for a HeLa and b LNCaP. Error bars are the 95% confidence interval from three independent experiments. Cells were irradiated with 0, 2, 5, and 10 Gy using a 6 MV linear accelerator. c, d Normalized 53BP1 foci per nuclear area 24 h following radiation in c HeLa and b LNCaP. Error bars are the 95% confidence interval from at least 50 nuclei from three experiments. ns indicates no significance, * indicates 0.01 < p < 0.05, ** indicates 0.001 < p < 0.01, *** indicates 0.0001 < p< 0.001, **** indicates p < 0.0001

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