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Fig. 7 | Cancer Nanotechnology

Fig. 7

From: Polymer lipid hybrid nanoparticles encapsulated with Emodin combined with DOX reverse multidrug resistance of breast cancer via IL-6/JAK2/STAT3 signaling pathway

Fig. 7

E-PLNs reversed IL-6 induced EMT, invasion and MDR of MCF-7/ADR cells. A-B. Expression of EMT related proteins under no pretreatment; C-D. Cell invasion under no pretreatment; E–F. Expression of EMT related proteins in the presence of IL-6; G-H. Cell invasion in the presence of; I-J. Expression of EMT-related proteins in the presence of AG490; K-L. Cell invasion in the presence of AG490. The numerical data (B, D, F, H, J, L, N, P) were presented as the mean ± SD (n = 3). One-way ANOVA followed by the Bonferroni post hoc test (B, D, F, H, J, L, N, P) were used for statistical significance analysis. All experiments were repeated three times. *p < 0.05, **p < 0.01, ***p < 0.001, ns means no significance.

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Cancer Nanotechnology

ISSN: 1868-6966

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