Fig. 4
Overexpression of MSLN promotes cell migration and invasion. Wound healing assay (A) and quantification of migration rate at different time points (B) in NC, LV-NC, and LV-MSLN cells. **p < 0.01, vs. NC. C Representative images of Transwell migration assay and the number of migrating cells as well as OD Values (D). E Transwell invasion assay and quantitative analysis of invasive cells together with OD values (F). **p < 0.01, vs. LV-MSLN. G: Survival curves of tumor-bearing nude mice with NC, LV-NC, and LV-MSLN cells. Scale bar: 50 µm. One-way ANOVA with Tukey’s multiple comparisons test (B, D, F)