Fig. 6
Targeted MRI examination of FSPM in vitro. A T2WI and T2 mapping MRI examinations of FSPMs with different iron ion concentrations (0, 1, 10, 20, 40, and 60 μg/mL) after incubation with A549, MeT-5A, and MPM cells. B, C T2 value and T2 signal intensity changes under the Fe3+ gradient concentration. FSP, Fe3O4@SiO2-PEG; FSPM, Fe3O4@SiO2-PEG-MSLN. *p < 0.05, vs. 0 μg/mL; # p < 0.05 vs. other groups. One-way ANOVA with Tukey’s multiple comparisons test (B, C)