Fig. 7

Targeted MRI examination of FSPM in vivo. A, C, and E 42 days after tumor transplantation. In vivo T2WI and T2 mapping of nude mice at different time points (0, 0.5, 1.5, 2.5, and 3.5 h) after injection of saline, FSP, and FSPM in A549, MSTO-211H, and H226 groups. B, D, and F Corresponding T2 signal intensity and T2 value changes in tumor tissues (lower). *p < 0.05, vs. before injection. One-way ANOVA with Tukey’s multiple comparisons test (B, D, F), n = 3