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Fig. 7 | Cancer Nanotechnology

Fig. 7

From: Novel nanotherapeutics for cancer immunotherapy by albumin nanoparticles functionalized with PD-1 and PD-L1 aptamers

Fig. 7

Immune cytotoxicity against PDL1-expressing MDA-MB-231 cells with various treatments. MDA-MB-231 cells were co-cultured with PBMC in vitro, and treated with free PD1 aptamers, free PDL1 aptamers, PD1-NP, PDL1-NP, a combination of PD1-NP and PDL1-NP, or PD1-NP-PDL1. Seventy-two hours later, the cells were washed thrice with PBS and the viability of tumor cells was evaluated by MTS assay. Untreated MDA-MB-231 cells served as the control (n = 6, mean ± SEM)

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