Fig. 6

Activity of AT-MSCs/Pt-8AQ secretome on U87-MG 3D spheroids. A RTq-PCR of Caspase-3 on untreated spheroids (CTRL) or treated 24 h with Pt-8AQ 5 µM or the secretome of AT-MSCs loaded with Pt-8AQ. The values are expressed as mean of three replicates ± SEM. B MTT assay on U87-MG spheroids treated 24 h with Pt-8AQ 5 µM or AT-MSCs/Pt-8AQ secretome, compared to untreated control spheroids. Data are expressed as optical density (OD) at 545 nm and are the mean ± SEM of three replicates