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Fig. 6 | Cancer Nanotechnology

Fig. 6

From: Novel nanoparticle CS-C60-Fe3O4 magnetically induces tissue-specific aggregation and enhances thermal ablation of hepatocellular carcinoma

Fig. 6

CS-C60-Fe3O4 up-regulates the antitumor activity of thermal ablation on HCC tumor tissue. MHCC97-H cells were obtained in culture, and after inoculation of nude mice to form subcutaneous tumor tissue, CS-C60-Fe3O4 was administered by tail vein injection and magnetic field induced C60 enrichment in the tumor tissue followed by thermal ablation. A RFA; B MWA) (including CS-C60-Fe3O4 alone or RFA and MWA alone), and thereafter periodically Tumor volumes were measured to plot tumor growth curves. Tumor weights were measured and tumor tissue samples were subjected to western blotting. The expression levels of TFR1, ALOX15, and GPX4 were examined using their respective antibodies. Actin was used as the endogenous control

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