Fig. 4
A In vitro cytotoxic effects of empty niosomes (N), DOX + CIS, DOX + CIS-Nio, and DOX + CIS-Nio@PEG–FA in A2780 cell line; B in vitro cytotoxic effects of empty niosomes (N), DOX + CIS, DOX + CIS-Nio, and DOX + CIS-Nio@PEG–FA in MCF-7 cells; C comparison between IC50 values of all samples in A2780 cells in 48 and 72 h; D comparison between IC50 values of all samples in MCF7 cells in 48 and 72 h; E in vitro cytotoxic effects of empty niosomes (N), DOX + CIS, DOX + CIS-Nio, and DOX + CIS-Nio@PEG–FA in HFF cells; F IC50 values of all samples in HFF cells in 72 h (Data are represented as mean ± SD and n = 3; ****P < 0.0001, ***P < 0.001, **P < 0.01, *P < 0.05). The control sample refers to the cells without treatment