Fig. 4From: HepG2 exosomes coated luteolin nanoparticles remodeling hepatic stellate cells and combination with sorafenib for the treatment of hepatocellular carcinomaIn vitro cytotoxicity of luteolin and sorafenib at different concentrations to HepG2 cells and LX2 cells. A Cell viability of LX2 cells treated with luteolin with increasing dosage for 24 h. B Cell viability of LX2 cells treated with sorafenib for 24 h. C Cell viability of HepG2 cells treated with sorafenib for 48 h measured by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) assay. IC50 and IC80 were determined by dose–response curves using GraphPad Prism software (Version 8.0.1). Data are represented as mean ± SD (n = 5)Back to article page