Table 1 Effects of different luteolin/PLGA ratios on particle size, Zeta potential, DLC and EE of Lut-NPs (n = 3, mean ± SD)
NO | Luteolin/PLGA (w/w) | Particle size (nm) | Zeta potential (mV) | DLC(%) | EE (%) | Luteolin concentration (mg/mL) | |
|---|---|---|---|---|---|---|---|
(%) | (mg/mg) | ||||||
P1 | 5 | 0.526/10 | 112 ± 4 | − 39 ± 1 | 1.4 ± 0.1 | 28.6 ± 1.9 | 0.15 ± 0.01 |
P2 | 4 | 0.420/10 | 115 ± 5 | − 37 ± 1 | 2.3 ± 0.2 | 57.1 ± 3.6 | 0.24 ± 0.02 |
P3 | 3 | 0.310/10 | 115 ± 3 | − 33 ± 3 | 2.0 ± 0.0 | 64.7 ± 1.0 | 0.20 ± 0.00 |
P4 | 4 | 0.210/5 | 93 ± 7 | − 33 ± 2 | 2.5 ± 0.1 | 53.6 ± 2.9 | 0.11 ± 0.01 |
P5 | 4 | 0.840/20 | Precipitation | ||||