Fig. 5
A Evaluation of the photothermal effect. The heating curves of A Fe3O4-CMSC-5FU (30, 75, 175 and 350 mg mL−1) B Fe3O4 (30, 75, 175 and 350 mg mL−1) as a function of irradiation, time under 808 nm laser irradiation at a power density of 600 mW/cm2. C (i) T1 relaxation rate plotted as a function of Fe3O4-CMSC-5FU concentration and 1/T1 s–1, (ii) T1-weighted MRI images (1.5T, spin-echo sequence: repetition time TR = 1550 ms, echo time TE = 10 ms) of Fe3O4-CMSC-5FU nanoparticles at various concentrations and 1/T2 s–1 at 27 °C. D (i) T2 relaxation rate plotted as a function of Fe3O4-CMSC-5FU concentration (ii) T2-weighted MRI images (1.5T, spin-echo sequence: repetition time TR = 1600 ms, echo time TE = 110 ms) of Fe3O4-CMSC-5FU nanoparticles at various concentration at 27 °C