Fig. 2
From: Hypobaric hypoxia exposure regulates tissue distribution of nanomedicine for enhanced cancer therapy
Effects of HH and HBO exposure on the pharmacokinetics of PTX-LPs. Photographs of (A) HH and (B) HBO chambers. Plasma drug concentration of free PTX and PTX-LPs after (C) the 1st treatment and (D) the 2st treatment. Healthy mice were intravenously injected with free PTX and PTX-LPs (5 mg PTX/kg body weight) and immediately subjected to HH or HBO exposure for 1.5 h. Data were presented as mean ± SEM (n = 4). *p < 0.05 and **p < 0.01