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  1. Although liposomes have improved patient safety and the pharmacokinetic profile of free drugs, their therapeutic efficacy has only shown marginal improvement. The incorporation of active-targeted ligands to en...

    Authors: Rezvan Yazdian-Robati, Ehsan Amiri, Hossein Kamali, Aysun Khosravi, Seyed Mohammad Taghdisi, Mahmoud Reza Jaafari, Mohammad Mashreghi and Seyedeh Alia Moosavian
    Citation: Cancer Nanotechnology 2023 14:84
  2. Immune checkpoint blockade (ICB) has achieved unprecedented success in inhibiting the progression and metastasis of many cancers. However, ICB regents as a single treatment have a relatively low overall respon...

    Authors: Yeteng Mu, Yuxin Fan, Lianping He, Nannan Hu, Han Xue, Xingang Guan and Zhijian Zheng
    Citation: Cancer Nanotechnology 2023 14:83
  3. Tumor microparticles (T-MPs) are vesicles released from tumor cells when they receive apoptotic or stimuli signals. T-MPs, which contain some proteins, lipids and nucleic acids from tumor cells, contribute to ...

    Authors: Weiwei Sun, Pingwei Xu, Pengtao Pan, Sheng Guo, Rui Liu, Guojie Ji, Huanhuan Hu, Weidong Li and Lili Dai
    Citation: Cancer Nanotechnology 2023 14:82
  4. Artesunate (ART) has great value in the field of tumor therapy. Interestingly, in this study, we found that ART could obviously induce ferroptosis in hepatocellular carcinoma (HCC) cells, but its low water sol...

    Authors: Dengyun Nie, Ting Guo, Xinyu Zong, Wenya Li, Yinxing Zhu, Miao Yue, Min Sha and Mei Lin
    Citation: Cancer Nanotechnology 2023 14:81
  5. Much in vitro research on the applicability of gold nanoparticles (GNPs) in cancer treatment has been focused on two-dimensional (2D) monolayer models. To improve this, we explored the effect of the combinatio...

    Authors: Kyle Bromma, Wayne Beckham and Devika B. Chithrani
    Citation: Cancer Nanotechnology 2023 14:80
  6. In the present era, we are facing different health problems mainly concerning with drug resistance in microorganisms as well as in cancer cells. In addition, we are also facing the problems of controlling oxid...

    Authors: Pramod C. Mane, Deepali D. Kadam, Ashok N. Khadse, Aditya R. Chaudhari, Supriya P. Ughade, Sachin B. Agawane and Ravindra D. Chaudhari
    Citation: Cancer Nanotechnology 2023 14:79

    The Publisher Correction to this article has been published in Cancer Nanotechnology 2023 14:85

  7. PEGylated nanoparticles (PEG-NPs) are not effective for hematologic malignancies as they lack the enhanced permeability and retention effect (EPR effect). Tumor-targeted PEG-NPs can systemically track lymphoma...

    Authors: Huei-Jen Chen, Yi-An Cheng, Yu-Tung Chen, Chia-Ching Li, Bo-Cheng Huang, Shih-Ting Hong, I.-Ju Chen, Kai-Wen Ho, Chiao-Yun Chen, Fang-Ming Chen, Jaw-Yuan Wang, Steve R. Roffler, Tian-Lu Cheng and Dung-Ho Wu
    Citation: Cancer Nanotechnology 2023 14:78
  8. Bee pollen extract (BPE)-based polymer nanoparticles (BPENP) were fabricated using bovine serum albumin (BSA) and targeted with folic acid and were further characterized. Mice groups are: Group 1 received sali...

    Authors: Elsayed I. Salim, Magdy E. Mahfouz, Eman A. Eltonouby, Nemany A. N. Hanafy and Ezar H. Hafez
    Citation: Cancer Nanotechnology 2023 14:77
  9. Engineering nanotherapeutics have been extensively studied for cancer therapy. However, the therapeutic efficacy is still severely restricted by biophysiological barriers and intracellular accumulation. Althou...

    Authors: Xinyue Xing, Yuying Zeng, Wanqing Zhong, Wendai Cheng, Chengxin Zhou, Xiaoxu Lu and Liyun Zhong
    Citation: Cancer Nanotechnology 2023 14:76
  10. Radiotherapy (RT) is an essential component in the treatment regimens for many cancer patients. However, the dose escalation required to improve curative results is hindered due to the normal tissue toxicity t...

    Authors: Nolan Jackson, Iona Hill, Abdulaziz Alhussan, Kyle Bromma, Jessica Morgan, Belal Abousaida, Yasmin Zahra, Yuri Mackeyev, Wayne Beckham, Steven Herchko, Sunil Krishnan and Devika Basnagge Chithrani
    Citation: Cancer Nanotechnology 2023 14:75
  11. Breast cancer is the neoplastic disease with the highest incidence and mortality in the female population worldwide. Treatment remains challenging due to various factors. Therefore, it is of great importance t...

    Authors: Camila Sales Nascimento, Naiara Clemente Tavares, Izabella Cristina Andrade Batista, Mônica Maria Magalhães Caetano, Eneida Santos de Oliveira, Stella Garcia Colombarolli, Anna Carolina Pinheiro Lage, Rodrigo Corrêa-Oliveira, Érica Alessandra Rocha Alves, Celso Pinto de Melo and Carlos Eduardo Calzavara-Silva
    Citation: Cancer Nanotechnology 2023 14:74
  12. Prostate cancer (PCa) is one of the fatal illnesses among males globally. PCa-treatment does not include radiotherapy. Chemotherapy eventually causes drug resistance, disease recurrence, metastatic advancement...

    Authors: Ashique Al Hoque, Debasmita Dutta, Brahamacharry Paul, Leena Kumari, Iman Ehsan, Moumita Dhara, Biswajit Mukherjee, Mohiuddin Quadir, Benny Abraham Kaipparettu, Soumik Laha and Shantanu Ganguly
    Citation: Cancer Nanotechnology 2023 14:73
  13. Cisplatin (CP) is the first-line standard of care for bladder cancer. However, a significant percentage of advanced bladder cancer patients are ineligible to receive standard CP treatment, due to the drug’s to...

    Authors: Yoray Sharon, Menachem Motiei, Chen Tzror-Azankot, Tamar Sadan, Rachela Popovtzer and Eli Rosenbaum
    Citation: Cancer Nanotechnology 2023 14:72
  14. Newcastle disease virus (NDV) Lasota strain has proven oncolytic activity. One shortcoming associated with this treatment modality is the immune neutralization of the virus in body, mediated by natural killer ...

    Authors: Kousain Kousar, Faiza Naseer, Maisa S. Abduh, Sadia Anjum and Tahir Ahmad
    Citation: Cancer Nanotechnology 2023 14:71
  15. In the current treatment of non-small cell lung cancer (NSCLC), traditional chemotherapy causes high toxicity, so it is necessary to develop safe chemical drug delivery vehicles clinically. Chemotherapy monoth...

    Authors: Tiantian Tan, Yuxin Feng, Weimin Wang, Rongrong Wang, Liyan Yin, Yiying Zeng, Zhaowu Zeng and Tian Xie
    Citation: Cancer Nanotechnology 2023 14:70
  16. The use of nanocarriers to improve the targeting of treatment plays a key role in the treatment of many diseases, including cancer. This study was carried out to synthesize graphene oxide (GO) containing 6-gin...

    Authors: Angham Hakim Abdulzahra Al-Janabi, Nasim Hayati Roodbari and Masoud Homayouni Tabrizi
    Citation: Cancer Nanotechnology 2023 14:69
  17. Chlorin e6 trisodium salt (Ce6) is a newly developed hydrophilic photosensitizer designed to mediate anticancer photodynamic therapy (PDT). The response of different cancer types and strategies to boost antica...

    Authors: Sara A. Abdel Gaber, Herbert Stepp, Mahmoud H. Abdel Kader and Mika Lindén
    Citation: Cancer Nanotechnology 2023 14:67
  18. Owing to the complexity of cancer, a synergistic combination of chemotherapy and gene therapy can be a promising therapeutic strategy. This study aimed to use stem cell membrane (SCM)-camouflaged polydopamine ...

    Authors: Kunzhe Wu, Zhongsheng Zhou, Te Liu, Chunkang Liu, Xupeng Mu and Jinlan Jiang
    Citation: Cancer Nanotechnology 2023 14:66
  19. The in vivo anticancer potential of vincristine (VC) loaded, thiolated chitosan-based nanoformulation (NFs) with an outer hyaluronic acid (VC-loaded in TCs-HA) coating was studied in prostate cancer (PC) xenog...

    Authors: Faiza Naseer, Kousain Kousar, Maisa S. Abduh, Sadia Anjum and Tahir Ahmad
    Citation: Cancer Nanotechnology 2023 14:65

    The Correction to this article has been published in Cancer Nanotechnology 2023 14:68

  20. Triple-negative breast cancer (TNBC) remains a difficult breast cancer subtype to treat as it exhibits a particularly aggressive behavior. The dysregulation of distinct signaling pathways underlies this aggres...

    Authors: Vladimir Mulens-Arias, Yadileiny Portilla, Sonia Pérez-Yagüe, Raquel Ferreras-Martín, M. Elena Martín, Victor M. González and Domingo F. Barber
    Citation: Cancer Nanotechnology 2023 14:64
  21. Extracellular vesicles (EVs) have tremendous potential as nano/micron-sized drug delivery carriers. Their physical, chemical and biological characteristics distinguish them as unique carriers with specific ph...

    Authors: Hui Luo, Jing Jin, Jiajia Jin, Kecheng Lou, Hailan He, Shangzhi Feng, Fei Zeng and Junrong Zou
    Citation: Cancer Nanotechnology 2023 14:63
  22. The vascular endothelial growth factor receptor-2 (VEGFR-2) plays an important role in melanoma development and progression. Peptide vaccines have shown great potential in cancer immunotherapy by targeting VEG...

    Authors: Fatemeh Zahedipour, Parvin Zamani, Mohammad Mashreghi, Mojgan Astaneh, Mojtaba Sankian, Atefeh Amiri, Khadijeh Jamialahmadi and Mahmoud Reza Jaafari
    Citation: Cancer Nanotechnology 2023 14:62
  23. As a radiosensitizing agent in magnetic resonance imaging (MRI), gadolinium is disadvantageous in that it confers a rather high toxicity and low longitudinal comfort time (r1). We hypothesized that gadolinium whe...

    Authors: Azadeh Amraee, Zahra Alamzadeh, Rasoul Irajirad, Abolfazl Sarikhani, Habib Ghaznavi, Hossein Ghadiri Harvani, Seied Rabi Mahdavi, Sakine Shirvalilou and Samideh Khoei
    Citation: Cancer Nanotechnology 2023 14:61
  24. Gallic acid is a natural antioxidant present in many plants such as tea, sumac, gallnut and other plants. This naturally occurring gallic acid is known to exhibit auto-oxidation under certain conditions, gener...

    Authors: Ahmed. A. G. El-Shahawy, Esam M. Dief, S. I. El-Dek, A. A. Farghali and Fatma I. Abo El-Ela
    Citation: Cancer Nanotechnology 2023 14:60
  25. Using a chemotherapeutic agent, such as doxorubicin (DOX), with a natural agent, such as silibinin (Sili), is highly valuable to minimize systemic toxicity. However, Sili and DOX face disadvantages, such as lo...

    Authors: Maryamsadat Shahidi, Bibi Fatemeh Haghiralsadat, Omid Abazari, Mahdie Hemati, Parisa Dayati, Hossein Zarei Jaliani, Najmeh Sadat Hosseini Motlagh, Seyed Morteza Naghib and Ali Moradi
    Citation: Cancer Nanotechnology 2023 14:59
  26. Glioma is the most prevalent type of primary brain tumor, and glioblastoma multiforme (GBM) is the highest and most deadly type of primary central nervous system (CNS) tumor, affecting a significant number of ...

    Authors: Dongdong Liu, Xingliang Dai, Zhenchao Tao, Hu Zhou, Wenqing Hong, Haisheng Qian, Hongwei Cheng and Xianwen Wang
    Citation: Cancer Nanotechnology 2023 14:58
  27. The lack of efficacious treatments for clear cell renal cell carcinoma (ccRCC) has led to a poor 5-year survival rate. Here, we found that the expression of ADAM metallopeptidase with thrombospondin type 1 mot...

    Authors: Enyang Zhao, Bo Geng, Ran Tao, Bosen You, Yunli Liu, Wenbin Hou, Wanhui Wang, Changlin Wang and Xuedong Li
    Citation: Cancer Nanotechnology 2023 14:57
  28. Zinc oxide nanoparticles (ZnO NPs) have been known as a therapeutic agent and drug delivery system for treating various diseases, including infectious diseases and cancer. However, due to the low biocompatibil...

    Authors: Qing Zhou, Li Zhang, Yujiao Li, Jiao Wang, Xiaolu He, Jieyu Zhang, Youbei Qiao, Hong Wu and Lin Zhu
    Citation: Cancer Nanotechnology 2023 14:56
  29. Cancer stem cells (CSCs) are of great diagnostic importance due to their involvement in tumorigenesis, therapeutic resistance, metastasis and relapse.

    Authors: Solmaz Sadi, Balal Khalilzadeh, Mahdi Mahdipour, Fatemeh Sokouti Nasimi, Ibrahim Isildak, Soodabeh Davaran, Mohammad-Reza Rashidi and Farhad Bani
    Citation: Cancer Nanotechnology 2023 14:55
  30. Combining the power of magnetic guidance and the biological activities of stem cells transformed into biohybrid microrobots holds great promise for the treatment of several diseases including cancer.

    Authors: Rebekah Anamarie Gundersen, Tianyuan Chu, Kiana Abolfathi, Serap Gokcen Dogan, Phoebe Elizabeth Blair, Nyasha Nago, Michael Hamblin, Greg Nicholas Brooke, Ralf Michael Zwacka, Ali Kafash Hoshiar and Andrea Mohr
    Citation: Cancer Nanotechnology 2023 14:54
  31. Tumor hypoxia is an important factor for developing resistance to radiation therapy (RT) and presents a bleak prognosis in cancer patients undergoing treatment for RT resistant hepatocellular carcinoma. Here, ...

    Authors: Reju George Thomas, Subin Kim, Raveena Nagareddy, Veena Vijayan, Ansuja Mathew Pullickal, Mee Sun Yoon, In Kyu Park and Yong Yeon Jeong
    Citation: Cancer Nanotechnology 2023 14:53
  32. The accurate diagnosis and treatment of cancer cell lesions need a high standard of detection technology. Fluorescent probes to perform cancer biomarker detection have become a popular research issue. However,...

    Authors: Yue He, Hongtao Rao, JingJing Wang, Ying Wu, Caiqin Han, Changchun Yan, Hunter Temple, Le Zhang, Wei Chen and Ying Liu
    Citation: Cancer Nanotechnology 2023 14:52
  33. Blocking the binding of PD-1/PD-L1 has become an effective strategy in inhibition of tumor immune escape. At present, it mainly depends on the employment of macromolecular antibodies, which target PD-1/PD-L1 p...

    Authors: Wenwen Ji, Bei Zhang, Xuetong Sun, Lijuan Ma, Xiangying Zhang, Wenhui Qian, Wenjuan Fu, Jianting Li and Dong Zhu
    Citation: Cancer Nanotechnology 2023 14:51
  34. Tumor angiogenesis, immunosuppression, and progression are all closely correlated with the tumor microenvironment (TME). Immune evasion is supported by both M2 phenotype tumor-associated macrophages (TAMs) and...

    Authors: Hongsheng Wang, Xinmeng Jin, Yinghua Gao, Xin He, Yiming Xu, Haoran Mu, Yafei Jiang, Zhuoying Wang, Chen Yu, Tao Zhang, Yingqi Hua, Zhengdong Cai, Jing Xu, Xiaojun Ma and Wei Sun
    Citation: Cancer Nanotechnology 2023 14:50
  35. This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing promising reconstituted proethoniosomes (PENs). The reconstituted PENs loaded with PTS were fabricated according to a 23 facto...

    Authors: Nemany A. N. Hanafy, Reham H. Abdelbadea, Abdelaziz E. Abdelaziz and Eman A. Mazyed
    Citation: Cancer Nanotechnology 2023 14:49
  36. Tyrosine kinase inhibitors (TKI) have been highlighted for the therapy of non-small-cell lung cancer (NSCLC), due to their capability of efficiently blocking signal pathway of epidermal growth factor receptor ...

    Authors: Mingwei Wang, Haiyan Huang, Zilong Zhong, Xinyue Chen, Yuan Fang, Shenxin Chen, Zhiyao Qi, Danrong Yang, Junyou Wang and Wei Bian
    Citation: Cancer Nanotechnology 2023 14:48
  37. Gadolinium-based nanoparticles (GdNPs) are clinically used agents to increase the radiosensitivity of tumor cells. However, studies on the mechanisms and biological modeling of GdNP radio-enhancement are still...

    Authors: Jianan Wu, Xiaohan Xu, Ying Liang, Tujia Chen, Enzhuo Quan and Luhua Wang
    Citation: Cancer Nanotechnology 2023 14:47
  38. A novel magnetic-targeted pH-responsive intelligent drug carrier based on hollow mesoporous structured NiFe2O4 nanospheres was designed and developed for potential anticancer treatment in the present study. The h...

    Authors: Qing Qi, Hui Zhang, Mengru Liu, Shujing Qi, Zhongchao Huo, Yingying Ma, Zhongqiang Zhang, Yongchang Lu, Xiongwei Qi, Shuai Han and Guangshuo Wang
    Citation: Cancer Nanotechnology 2023 14:46
  39. Developing high-performance sensing frameworks for diagnosing anaplastic changes is the subject of debate. The lack of on-time diagnosis in patients with suspicious cancers can affect the prognosis and surviva...

    Authors: Hassan Nasrollahpour, Balal Khalilzadeh, Reza Rahbarghazi, Nevin Erk, Mohammad-Reza Rashidi and Abdolhossein Naseri
    Citation: Cancer Nanotechnology 2023 14:45
  40. In the present study, a magnetohyperthermia (MH)-based therapy is introduced as an effective treatment for deep-seated tumors especially glioma, which combines the magnetothermal effect and the reactive oxygen...

    Authors: Roghayeh Sheervalilou, Samideh Khoei, Sepideh Khoee, Milad Shirvaliloo, Elaheh Sadri, Sakine Shirvalilou and Mina Goudarzi
    Citation: Cancer Nanotechnology 2023 14:44
  41. Bone metastasis is the main cause of death in patients with prostate cancer (PCa), but there lacks effective treatment method. Immunotherapy shows new hopes for bone metastatic PCa patients, while the efficacy...

    Authors: Shu Huang, Jun Yuan, Yong Xie, Kai Qing, Zeya Shi, Guanyu Chen, Jie Gao, Haoxiang Tan and Wenhu Zhou
    Citation: Cancer Nanotechnology 2023 14:43
  42. Nano-Zinc oxide (Nano-ZnO) has been increasingly applied in agriculture, industry and biomedicine. However, the genotoxic effects of Nano-ZnO and the underlying mechanisms remain incompletely clear.

    Authors: Meiling Zhou, Liang Xiao, Jing Jin, Yin Wang, Peiyu Guo, Jinhua Luo, Magdalena Skonieczna and Ruixue Huang
    Citation: Cancer Nanotechnology 2023 14:42
  43. For the treatment of triple-negative breast cancer (TNBC), without expression of estrogen, progesterone and HER2 receptors, specific treatment guideline is still under criticism, especially in tumor hypoxia. B...

    Authors: Majid Sharifi, Rasoul Kheradmandi and Morteza Alizadeh
    Citation: Cancer Nanotechnology 2023 14:41
  44. Fenton reaction-based chemodynamic therapy (CDT) is regarded as a highly tumor-specific treatment modality due to its intrinsic tumor microenvironment (TME)-specific targeting properties, such as high amounts ...

    Authors: Laya Khoshtabiat, Azadeh Meshkini and Maryam M. Matin
    Citation: Cancer Nanotechnology 2023 14:40
  45. Increasing evidence indicates that radiotherapy (RT) has synergistic inhibitory efficiency with immunotherapy agents in multiple cancers and enhances abscopal effects by regulating the innate immune response, ...

    Authors: Dehua Lu, Yanming Xu, Xiaodong Yang, Ying Li, Mengqing Li, Yuanyuan Zheng, Yuenan Wang, Weihu Wang, Shubin Wang, Jing Gao and Yajie Liu
    Citation: Cancer Nanotechnology 2023 14:39
  46. Overwhelming Fe accumulation in tumor arouses strong oxidative stress. To benefit the cancer patients, Fe(II) delivered by carbon nanoparticles-Fe(II) complex (CNSI-Fe) should be visualized to ensure the succe...

    Authors: Ping Xie, Yuanfang Huang, Kexin Tang, Xian Wu, Cheng Zeng, Sheng-Tao Yang and Xiaohai Tang
    Citation: Cancer Nanotechnology 2023 14:38
  47. Colorectal cancer (CRC) is the third most diagnosed tumor worldwide, with a very high mortality rate, second only to lung cancer. Current treatments, such as surgery, chemotherapy or radiotherapy, are not effe...

    Authors: Luisa Racca, Giada Rosso, Marco Carofiglio, Sharmila Fagoonee, Giulia Mesiano, Fiorella Altruda and Valentina Cauda
    Citation: Cancer Nanotechnology 2023 14:37
  48. Tumor microparticles (T-MPs) are considered as a tumor vaccine candidate. Although some studies have analyzed the mechanism of T-MPs as tumor vaccine, we still lack understanding of how T-MPs stimulate a stron...

    Authors: Weiwei Sun, Lili Dai, Yuqing Cao, Pengtao Pan, Lijuan Zhi, Xinke Wang, Xinzhong Yuan, Zi Gao, Sheng Guo, Guoyan Liu, Junlei Yin, Liangliang Xie, Liping Wang, Yanling Wang, Wensheng Li, Hong Li…
    Citation: Cancer Nanotechnology 2023 14:34

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