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  1. Blocking the binding of PD-1/PD-L1 has become an effective strategy in inhibition of tumor immune escape. At present, it mainly depends on the employment of macromolecular antibodies, which target PD-1/PD-L1 p...

    Authors: Wenwen Ji, Bei Zhang, Xuetong Sun, Lijuan Ma, Xiangying Zhang, Wenhui Qian, Wenjuan Fu, Jianting Li and Dong Zhu
    Citation: Cancer Nanotechnology 2023 14:51
  2. Tumor angiogenesis, immunosuppression, and progression are all closely correlated with the tumor microenvironment (TME). Immune evasion is supported by both M2 phenotype tumor-associated macrophages (TAMs) and...

    Authors: Hongsheng Wang, Xinmeng Jin, Yinghua Gao, Xin He, Yiming Xu, Haoran Mu, Yafei Jiang, Zhuoying Wang, Chen Yu, Tao Zhang, Yingqi Hua, Zhengdong Cai, Jing Xu, Xiaojun Ma and Wei Sun
    Citation: Cancer Nanotechnology 2023 14:50
  3. This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing promising reconstituted proethoniosomes (PENs). The reconstituted PENs loaded with PTS were fabricated according to a 23 facto...

    Authors: Nemany A. N. Hanafy, Reham H. Abdelbadea, Abdelaziz E. Abdelaziz and Eman A. Mazyed
    Citation: Cancer Nanotechnology 2023 14:49
  4. Tyrosine kinase inhibitors (TKI) have been highlighted for the therapy of non-small-cell lung cancer (NSCLC), due to their capability of efficiently blocking signal pathway of epidermal growth factor receptor ...

    Authors: Mingwei Wang, Haiyan Huang, Zilong Zhong, Xinyue Chen, Yuan Fang, Shenxin Chen, Zhiyao Qi, Danrong Yang, Junyou Wang and Wei Bian
    Citation: Cancer Nanotechnology 2023 14:48
  5. Gadolinium-based nanoparticles (GdNPs) are clinically used agents to increase the radiosensitivity of tumor cells. However, studies on the mechanisms and biological modeling of GdNP radio-enhancement are still...

    Authors: Jianan Wu, Xiaohan Xu, Ying Liang, Tujia Chen, Enzhuo Quan and Luhua Wang
    Citation: Cancer Nanotechnology 2023 14:47
  6. A novel magnetic-targeted pH-responsive intelligent drug carrier based on hollow mesoporous structured NiFe2O4 nanospheres was designed and developed for potential anticancer treatment in the present study. The h...

    Authors: Qing Qi, Hui Zhang, Mengru Liu, Shujing Qi, Zhongchao Huo, Yingying Ma, Zhongqiang Zhang, Yongchang Lu, Xiongwei Qi, Shuai Han and Guangshuo Wang
    Citation: Cancer Nanotechnology 2023 14:46
  7. Developing high-performance sensing frameworks for diagnosing anaplastic changes is the subject of debate. The lack of on-time diagnosis in patients with suspicious cancers can affect the prognosis and surviva...

    Authors: Hassan Nasrollahpour, Balal Khalilzadeh, Reza Rahbarghazi, Nevin Erk, Mohammad-Reza Rashidi and Abdolhossein Naseri
    Citation: Cancer Nanotechnology 2023 14:45
  8. In the present study, a magnetohyperthermia (MH)-based therapy is introduced as an effective treatment for deep-seated tumors especially glioma, which combines the magnetothermal effect and the reactive oxygen...

    Authors: Roghayeh Sheervalilou, Samideh Khoei, Sepideh Khoee, Milad Shirvaliloo, Elaheh Sadri, Sakine Shirvalilou and Mina Goudarzi
    Citation: Cancer Nanotechnology 2023 14:44
  9. Bone metastasis is the main cause of death in patients with prostate cancer (PCa), but there lacks effective treatment method. Immunotherapy shows new hopes for bone metastatic PCa patients, while the efficacy...

    Authors: Shu Huang, Jun Yuan, Yong Xie, Kai Qing, Zeya Shi, Guanyu Chen, Jie Gao, Haoxiang Tan and Wenhu Zhou
    Citation: Cancer Nanotechnology 2023 14:43
  10. Nano-Zinc oxide (Nano-ZnO) has been increasingly applied in agriculture, industry and biomedicine. However, the genotoxic effects of Nano-ZnO and the underlying mechanisms remain incompletely clear.

    Authors: Meiling Zhou, Liang Xiao, Jing Jin, Yin Wang, Peiyu Guo, Jinhua Luo, Magdalena Skonieczna and Ruixue Huang
    Citation: Cancer Nanotechnology 2023 14:42
  11. For the treatment of triple-negative breast cancer (TNBC), without expression of estrogen, progesterone and HER2 receptors, specific treatment guideline is still under criticism, especially in tumor hypoxia. B...

    Authors: Majid Sharifi, Rasoul Kheradmandi and Morteza Alizadeh
    Citation: Cancer Nanotechnology 2023 14:41
  12. Fenton reaction-based chemodynamic therapy (CDT) is regarded as a highly tumor-specific treatment modality due to its intrinsic tumor microenvironment (TME)-specific targeting properties, such as high amounts ...

    Authors: Laya Khoshtabiat, Azadeh Meshkini and Maryam M. Matin
    Citation: Cancer Nanotechnology 2023 14:40
  13. Increasing evidence indicates that radiotherapy (RT) has synergistic inhibitory efficiency with immunotherapy agents in multiple cancers and enhances abscopal effects by regulating the innate immune response, ...

    Authors: Dehua Lu, Yanming Xu, Xiaodong Yang, Ying Li, Mengqing Li, Yuanyuan Zheng, Yuenan Wang, Weihu Wang, Shubin Wang, Jing Gao and Yajie Liu
    Citation: Cancer Nanotechnology 2023 14:39
  14. Overwhelming Fe accumulation in tumor arouses strong oxidative stress. To benefit the cancer patients, Fe(II) delivered by carbon nanoparticles-Fe(II) complex (CNSI-Fe) should be visualized to ensure the succe...

    Authors: Ping Xie, Yuanfang Huang, Kexin Tang, Xian Wu, Cheng Zeng, Sheng-Tao Yang and Xiaohai Tang
    Citation: Cancer Nanotechnology 2023 14:38
  15. Colorectal cancer (CRC) is the third most diagnosed tumor worldwide, with a very high mortality rate, second only to lung cancer. Current treatments, such as surgery, chemotherapy or radiotherapy, are not effe...

    Authors: Luisa Racca, Giada Rosso, Marco Carofiglio, Sharmila Fagoonee, Giulia Mesiano, Fiorella Altruda and Valentina Cauda
    Citation: Cancer Nanotechnology 2023 14:37
  16. Cationic dyes are widely used as biomarkers for optical imaging. However, most of these are hydrophobic and cannot be employed in vivo without chemical conjugation or modification. Herein, we report for the fi...

    Authors: Nian Liu, Vipul Gujrati, Juan Pablo Fuenzalida Werner, Kanuj Mishra, Pia Anzenhofer, Andre C. Stiel, Gabriele Mettenleiter, Annette Feuchtinger, Axel Walch and Vasilis Ntziachristos
    Citation: Cancer Nanotechnology 2023 14:36
  17. Ti3C2 is a type of transition metal carbides and nitrides (MXenes) with high light-to-heat conversion efficiency property, which has been widely used in cancer treatment recently. In fact, active targeting delive...

    Authors: Zhiqiang Bai, Lu Zhao, Haidi Feng, Zhihui Xin, Chaoyu Wang, Zhixiong Liu, Maozhong Tian, Haifei Zhang, Yunfeng Bai and Feng Feng
    Citation: Cancer Nanotechnology 2023 14:35
  18. Tumor microparticles (T-MPs) are considered as a tumor vaccine candidate. Although some studies have analyzed the mechanism of T-MPs as tumor vaccine, we still lack understanding of how T-MPs stimulate a stron...

    Authors: Weiwei Sun, Lili Dai, Yuqing Cao, Pengtao Pan, Lijuan Zhi, Xinke Wang, Xinzhong Yuan, Zi Gao, Sheng Guo, Guoyan Liu, Junlei Yin, Liangliang Xie, Liping Wang, Yanling Wang, Wensheng Li, Hong Li…
    Citation: Cancer Nanotechnology 2023 14:34
  19. Radiotherapy is a major therapeutic modality for locally advanced head and neck cancer. However, the effectiveness of radiotherapy is hindered by resistance mechanisms, most notably hypoxia, leading to unfavou...

    Authors: Jie Feng, Varun Pathak, Niall M. Byrne, Tongchuan Wang, Cancan Yin, Reinhold J. Medina and Jonathan A. Coulter
    Citation: Cancer Nanotechnology 2023 14:33
  20. Colorectal malignant cells (CRC) are one of the world’s main causes of cancer mortality and morbidity. Notwithstanding the plenty of anti-CRC therapeutics, its prognosis remains not selective owing to cancer r...

    Authors: Ahmed A. Abd-Rabou, Ahmed M. Abdelaziz, Olfat G. Shaker and Ghada Ayeldeen
    Citation: Cancer Nanotechnology 2023 14:32
  21. Multiwalled carbon nanotubes (MWCNTs) are being widely investigated in multiple biomedical applications including, and not limited to, drug delivery, gene therapy, imaging, biosensing, and tissue engineering. ...

    Authors: Seung Soo Lee, Fatma Oudjedi, Andrew G. Kirk, Miltiadis Paliouras and Mark A. Trifiro
    Citation: Cancer Nanotechnology 2023 14:31
  22. Cancer is a major threat to human health; thus, early detection is imperative for successful management. Rapid diagnosis can be achieved by imaging primary (subcutaneous) tumors using fluorophores conjugated w...

    Authors: Sulaxna Pandey, Prakash Choudhary, Virendra Gajbhiye, Sachin Jadhav and Dhananjay Bodas
    Citation: Cancer Nanotechnology 2023 14:30
  23. Head and neck squamous cell carcinoma (SCC) is one of the most prevalent and deadly cancers worldwide. Even though surgical approaches, radiation therapy, and therapeutic agents are commonly used, the prognosi...

    Authors: Alberto Juan, Carmen Segrelles, Almudena del Campo-Balguerías, Iván Bravo, Ignacio Silva, Jorge Peral, Alberto Ocaña, Pilar Clemente-Casares, Carlos Alonso-Moreno and Corina Lorz
    Citation: Cancer Nanotechnology 2023 14:29
  24. Lung cancer is the leading cause of cancer mortality. As a heterogeneous disease, it has different subtypes and various treatment modalities. In addition to conventional surgery, radiotherapy and chemotherapy,...

    Authors: Yifan Liu, Wenxu Cheng, HongYi Xin, Ran Liu, Qinqi Wang, Wenqi Cai, Xiaochun Peng, Fuyuan Yang and HongWu Xin
    Citation: Cancer Nanotechnology 2023 14:28
  25. Chemotherapy resistance remains a major cause of therapeutic failure in gastric cancer. The combination of genetic material such as interference RNAs (iRNAs) to silence cancer-associated genes with chemotherap...

    Authors: Sofia Nascimento dos Santos, Dino Seigo Gushiken Junior, Jhonatas Pedrosa Marim Pereira, Natália Miranda Iadocicco, André Henrique Silva, Tatielle do Nascimento, Luís Alberto Pereira Dias, Flávia Rodrigues de Oliveira Silva, Eduardo Ricci-Junior, Ralph Santos-Oliveira and Emerson Soares Bernardes
    Citation: Cancer Nanotechnology 2023 14:26
  26. Intraperitoneal metastasis is one of the major causes of the high mortality rate of ovarian cancer. Bufalin (BU) is an effective component of the traditional Chinese medicine Chansu that exerts antitumor effec...

    Authors: Lan Xu, Shuli Ma, Bozhen Fan, Zeting Yuan and Peihao Yin
    Citation: Cancer Nanotechnology 2023 14:25
  27. Anethole (Ant) is a herbal compound with unique properties, which is limited in its clinical use due to its low solubility in aqueous solutions. Therefore, in this study, albumin nanocarrier modified with chit...

    Authors: Farzaneh Sadeghzadeh, Hasti Nasiraei Haghighi, Mahdiyeh Ghiyamati, Fateme Hajizadenadaf and Masoud Homayouni Tabrizi
    Citation: Cancer Nanotechnology 2023 14:24
  28. The presented research concerns the preparation of polymer nanoparticles (PNPs) for the delivery of doxorubicin. Several block and statistical copolymers, composed of ketoester derivative, N-isopropylacrylamide, ...

    Authors: Paweł Misiak, Katarzyna Niemirowicz-Laskowska, Karolina H. Markiewicz, Przemysław Wielgat, Izabela Kurowska, Robert Czarnomysy, Iwona Misztalewska-Turkowicz, Halina Car, Krzysztof Bielawski and Agnieszka Z. Wilczewska
    Citation: Cancer Nanotechnology 2023 14:23
  29. MicroRNAs, which can contribute to numerous cellular functions through post-transcriptional silencing, have become well-documented candidates for cancer treatment applications, particularly in chemo-resistant ...

    Authors: Najmeh Alsadat Abtahi, Saba Salehi, Seyed Morteza Naghib, Fatemeh Haghiralsadat, Mohammadmahdi Akbari Edgahi, Sadegh Ghorbanzadeh and Wei Zhang
    Citation: Cancer Nanotechnology 2023 14:22
  30. Clinical applications of RNA interference for cancer treatment and immune therapy require the development of simultaneous therapy and imaging systems for microRNA. This research was performed to fabricate the ...

    Authors: Seung-Hyun Yang, Hye Young Son, Mirae Park, Hyun Wook Rho, Hwunjae Lee and Yong-Min Huh
    Citation: Cancer Nanotechnology 2023 14:21
  31. Cancer treatment by inducing tumor cell immunogenic cell death (ICD) is critical for tumor therapy. However, ICD activation by single pathway is often limited in practical application due to its low efficiency...

    Authors: Yueyao Wu, Runtian Wang, Peiliang Shen, Weijia Zhou, Chao Chen, Kaiyong Yang, Jingjing Yang, Yujun Song, Xin Han and Xiaoxiang Guan
    Citation: Cancer Nanotechnology 2023 14:20
  32. Nanosized drug delivery systems have rapidly emerged as a promising approach to tumor therapy, which still have many challenges in clinical application. In this study, doxorubicin-loaded O-carboxymethyl chitos...

    Authors: Dong Meng, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Shan Xiao, Xiaoying Zhou, Yading Zhao, Xiaoxuan Wang and Jie Li
    Citation: Cancer Nanotechnology 2023 14:19
  33. Colorectal cancer is one of the prominent leading causes of fatality worldwide. Despite recent advancements within the field of cancer therapy, the cure rates and long-term survivals of patients suffering from...

    Authors: Anis Askarizadeh, Mohammad Mashreghi, Elaheh Mirhadi, Farshad Mirzavi, Vahid Heravi Shargh, Ali Badiee, Seyedeh Hoda Alavizadeh, Leila Arabi and Mahmoud Reza Jaafari
    Citation: Cancer Nanotechnology 2023 14:18
  34. Ferroptosis represents an innovative strategy to overcome the resistance of traditional cancer therapeutic through lethal lipid peroxidation leading to immunogenic cell death. However, the inefficiency of ferr...

    Authors: Ming Meng, Xia Zhang, Qian Li, Jingjing Han, Yu Chen, Haishi Qiao, Yonglin Yang and Xin Huang
    Citation: Cancer Nanotechnology 2023 14:17
  35. Pancreatic adenocarcinoma (PDAC) has a poor prognosis since often diagnosed too late. Dyslipidemia and hyperglycemia are considered risk factors, but the presence of the tumor itself can determine the onset of...

    Authors: Erica Quagliarini, Damiano Caputo, Roberto Cammarata, Giulio Caracciolo and Daniela Pozzi
    Citation: Cancer Nanotechnology 2023 14:16
  36. Hepatocellular carcinoma (HCC) is the leading cause of death worldwide. Nanoparticles allow early detection of tumor and delivery of chemotherapeutic drugs to the specific tumor site. This study aimed to asses...

    Authors: Wafaa Mansour, Shahira Fathy EL Fedawy, Shimaa Attia Atta, Rewan Mohsen Zarie, Nermeen Tayseer Aly Fouad, Sara Maher, Taghreed M. Hussein, Doaa Mohamed Abdel Aziz and Manal Kamel
    Citation: Cancer Nanotechnology 2023 14:14
  37. Graphene quantum dots (GQDs) are biocompatible nanoparticles employed in biomedical field, thanks to their size and photophysical properties. GQDs have shown the capability to cross biological barriers, includ...

    Authors: Giordano Perini, Valentina Palmieri, Ginevra Friggeri, Alberto Augello, Marco De Spirito and Massimiliano Papi
    Citation: Cancer Nanotechnology 2023 14:13
  38. Glioma treatment remains a challenge owing to unsatisfactory targeted chemotherapy, where the blood–brain barrier (BBB) hinders the efficient uptake of therapeutics into the brain. Vasculogenic mimicry (VM) fo...

    Authors: Qin Li, Jinglan Shen, Lingling Wu, Siyun Lei, Yimin Yang, Weide Xu, Ke Hao, Yi Zhang, Fei Kong, Wei Yang, Yaling Wang, Lina Peng, Kaiqiang Li and Zhen Wang
    Citation: Cancer Nanotechnology 2023 14:12
  39. Despite significant breakthroughs in diagnosis and treatment of colorectal cancer (CRC), the extent of morbidity and mortality secondary to CRC is still concerning. In this study, we evaluated the efficacy of ...

    Authors: Sakine Shirvalilou, Sepideh Khoee, Samideh Khoei, Mohammad Reza Karimi, Elaheh Sadri and Milad Shirvaliloo
    Citation: Cancer Nanotechnology 2023 14:11
  40. The study’s goal was to look into the protective properties of quercetin (QU) in natural form and QU nanoparticles-loaded chitosan nanoparticles (QU-CHSNPs) against cardiotoxicity. The ionotropic gelation appr...

    Authors: Asmaa. G. Soliman, Basant Mahmoud, Zienab E. Eldin, Ahmed A. G. El-Shahawy and Mohammed Abdel-Gabbar
    Citation: Cancer Nanotechnology 2023 14:10
  41. Myricetin is a flavonoid with anticancer properties. This study aimed to formulate myricetin in the form of solid lipid nanoparticles (SLN), decorated with chitosan (CS) and active-targeted with folic acid (FA...

    Authors: Niloufar Khatamian, Alireza Motavalizadehkakhky, Masoud Homayouni Tabrizi, Jamshid Mehrzad and Rahele Zhiani
    Citation: Cancer Nanotechnology 2023 14:9
  42. Hypoxia-mediated radioresistance is the main obstacle to the successful treatment of glioblastoma (GBM). Enhancing hypoxic radiosensitivity and alleviating tumor hypoxia are both effective means to improve the...

    Authors: Fangshi Zhao, Xiaoyi Wang, Wei Zhu, Dongju Zhao, Caihua Ye, Yanyan Guo and Yan Dou
    Citation: Cancer Nanotechnology 2023 14:8
  43. Nanomedicine offers great potentials for theranostic studies via providing higher efficacy and safety levels. This work aimed to develop and evaluate a new nanoplatform as a tumor theranostic probe.

    Authors: Mohamed M. Swidan, Basma M. Essa and Tamer M. Sakr
    Citation: Cancer Nanotechnology 2023 14:6
  44. Curcumin-loaded nanocomplexes (CNCs) previously demonstrated lower toxicity and extended release better than is the case for free curcumin. Here, we evaluated the efficacy of CNCs against opisthorchiasis-assoc...

    Authors: Chanakan Jantawong, Yaovalux Chamgramol, Kitti Intuyod, Aroonsri Priprem, Chawalit Pairojkul, Sirinapha Klungsaeng, Rungtiwa Dangtakot, Thatsanapong Pongking, Chutima Sitthirach, Porntip Pinlaor, Sakda Waraasawapati and Somchai Pinlaor
    Citation: Cancer Nanotechnology 2023 14:5
  45. To avoid the harmful side effects of cetuximab and improve its therapeutic efficacy, egg serum albumin (ESA) was used as a targeting drug carrier moiety for cancer therapy against Caco-2 colon cancer cells. Th...

    Authors: Elsayed I. Salim, Abeer M. Mosbah, F. A. Elhussiny, Nemany A. N. Hanafy and Y. Abdou
    Citation: Cancer Nanotechnology 2023 14:4
  46. Essential oils (EOs) are complex structures and possess several pharmacological effects. Nanomedicine offers a solution for their major limitations, including poor solubility, volatility, and non–controlled re...

    Authors: Khaled AbouAitah, Heba A. Hassan, Naglaa M. Ammar, Doha H. Abou Baker, Imane M. Higazy, Olfat G. Shaker, Ahmed A. A. Elsayed and Abeer M. E. Hassan
    Citation: Cancer Nanotechnology 2023 14:3
  47. Hepatoma is a serious public health concern. New attempts are urgently needed to solve this problem. Melittin, a host defense peptide derived from the venom of honeybees, has noteworthy hemolysis and non-speci...

    Authors: Xin Jin, Qing Yang, Guoli Wei, Jie Song and Zhenhai Zhang
    Citation: Cancer Nanotechnology 2023 14:2

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